ISSN 2277-4564
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INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES LETTERS       BI MONTHLY ISSUE (6 ISSUE/YEAR)
Editor in Chief :- B. Perianayagam, PhD
Assosiate Editor :-A. Pandurangan, Ph.D
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Volume- 6(2016) , Issue- 3
NEWS
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CURRENT ISSUE

Year- 2016 // Volume- 6 // Issue- 3 // Page No.- 51-54

Stem Cell therapy: Helping The Body Heal Itself

Sadasiva Rao G ,  B Nagamani, R Kasirao ,   SK Khyrun Baji, CH Ramana Reddy  
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Ultimately, every cell in the human body can be traced back to a fertilized egg that came into existence from the union of egg and sperm. But the body is made up of over 200 different types of cells, not just one. All of these cell types come from a pool of stem cells in the early embryo. During early development, as well as later in life, various types of stem cells give rise to the specialized or differentiated cells that carry out the specific functions of the body, such as skin, blood, muscle, and nerve cells. Over the past two decades, scientists have been gradually deciphering the processes by which unspecialized stem cells become the many specialized cell types in the body. Stem cells can regenerate themselves or produce specialized cell types. This property makes stem cells appealing for scientists seeking to create medical treatments that replace lost or damaged cells.
Somatic Stem Cells (SSCs), Embryonic Stem Cells (ESCs), Induced pluripotent stem cells (IPSCS).

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Year- 2016 // Volume- 6 // Issue- 3 // Page No.- 55-60

A Retrospective Study - Prevalence and Management of Pediatric Asthma in Muscat region

Hana Nasser Al Nadhairi, Hasna khalfan Al Shuaibi ,  Hajer Ahmed Al Rashdi, Amira Salim Al Khawaldi ,   AR.Mullaicharam, Nirmala Amaresh, P.J.Joseph Francis  
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Introduction: Asthma is the most common chronic lower respiratory disease observed in childhood throughout the world. Symptoms of wheezing, coughing or shortness of breath are common among infants and children. Objectives: To investigate the prevalence and management of pediatric asthma in Muscat region. Method: A retrospective study was carried out on 434 prescription pattern/ drugs used in the management of asthma from two public health centers in Muscat region from 2013 to 2015. Result: The study shows that the prevalence of asthma was more in boys (68%) than girls (31.1). The most common symptoms were coughing (28%), and fluticason and sulbutamol were the common medication used for treating asthma. Conclusion: The prevalence of pediatric asthma in children (1-12) years is high compared to previous year’s record. Male children were found at risk to get the asthma symptoms.
Pediatric Asthma, Prevalence in Muscat

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Year- 2016 // Volume- 6 // Issue- 3 // Page No.-

Simultaneous Estimation of Olmesartan and Clinidipine in Tablet Dosage Forms By RP-HPLC

D.R. Brahmareddy ,  P. Pavan Kumar Reddy,   A. Sampath  
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Background: A simple, precise, rapid and accurate RP HPLC method has been developed for the simultaneous estimation of olmesartan and clinidipine in tablet formulations. Methods: The chromatographic separation was achieved on a Waters 2965 ODS C18 column (250 mm x 4.6 mm, 5.0 µ particle size) using Acetonitrile:Buffer (60: 40 v/v) mobile phase. Ortho-phosphoric acid was used to adjust pH to 3.2, flow rate was 1ml/min and column was maintained at 300C. Quantification and linearity was achieved at 240 nm over the concentration range of 50 to 300µg/ml for olmesartan and 25 to 150µg/ml for clinidipine. Results: The method was validated for specificity, linearity, accuracy, precision, LOD, LOQ and robustness.
olmesartan, clinidipine, RP-HPLC

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