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The University of Western Australia

UWA Staff Profile

Ipsum Lorem

Professor Barry Iacopetta

Graduate Research Coordinator
Administration Unit (Surgery)

Contact details

Address: Administration Unit
The University of Western Australia (M507)
35 Stirling Highway
CRAWLEY WA 6009
Australia
Phone: +61 8 9346 2085
Fax: +61 8 9346 2416
Email: barry.iacopetta@uwa.edu.au

Qualifications

BSc PhD W.Aust.

Biography

Professor Barry Iacopetta completed his PhD at The University of Western Australia and postdoctoral work in Switzerland. Since returning to Australia, he has established a laboratory dedicated to translational cancer research. He collaborates with local, national and international colleagues in this field.

Key research

Epidemiology, genetics, pathology and molecular oncology research into colorectal cancer

Publications

Professor Iacopetta has produced more than 100 referred scholarly articles since 1992, and has also contributed to non-referred journals, and proceedings of conferences. Here is a selection of ten of his articles:

Smallwood, L, Allcock, R, van Bockxmeer, F, Warrington, N, Palmer, LJ,
Elsaleh H, Joseph D, Grieu F, Zeps N, Spry N, Iacopetta B 2000, ‘Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer’, The Lancet 355, pp. 1745–50.

van Rijnsoever M, Grieu F, Elsaleh H, Joseph D, Iacopetta B 2002 ‘Characterisation of colorectal cancers showing hypermethylation at multiple CpG islands’, GUT 51, pp. 797–802.

Iacopetta B 2002, ‘Are there two sides to colorectal cancer?’, Int J Cancer 101, pp. 403–8.

Iacopetta B 2006, ‘Methyl-group metabolism and the response of colorectal cancers to 5-Fluorouracil’, Critical Reviews in Oncogenesis 12, pp. 115–26.

Morris M, Platell C, Iacopetta B 2008, ‘Tumor-infiltrating lymphocytes and perforation in colon cancer predict positive response to 5-FU chemotherapy’, Clin Cancer Res 14, pp. 1413–17.

Iacopetta, B, Golledge, J, Norman, PE 2008, 'Polymorphisms of the matrix metalloproteinase 9 gene and abdominal aortic aneurysm', British Journal of Surgery, 95, pp. 1239–44.

Ang, PW, Toh, HB, Iacopetta, B, Soong, R 2008, 'An improved quality control for bisulfite-PCR-based DNA methylation analysis: cycle threshold value', Clinical Chemistry and Laboratory Medicine, 46, pp. 1117–21.

Soong, R, Amar, D, Liu, YQ, Eu, KW, Han, HC, Salto-Tellez, M, Iacopetta, B 2008, 'Denaturing high performance liquid chromatography for the detection of microsatellite instability using Bethesda and pentaplex marker panels', Diagnostic Molecular Pathology, 17, pp. 127–33.

Mok, MTS, Lawson, JS, Iacopetta, BJ, Whitaker, NJ 2008, 'Mouse mammary tumor virus-like env sequences in human breast cancer', International Journal of Cancer, 122, pp. 2864–70.

Kawakami, K, Ooyama, A, Ruszkiewicz, A, Jin, M, Watanabe, G, Moore, J, Oka, T, Iacopetta, B, Minamoto, T 2008, 'Low expression of gamma-glutamyl hydrolase mRNA in primary colorectal cancer with the CpG island methylator phenotype', British Journal of Cancer, 98, pp. 1555–61.

Roles, responsibilities and expertise