Table of Contents

2016 Month : December Volume : 2 Issue : 2 Page : 10-11

FIRST-EPISODE MANIA IN A 9-YEAR-OLD CHILD - A CASE REPORT.

Swapnil Agrawal1, Aftab Ahmed Khan2, Gayatri Mittal3, Rahila Quresh4, Ashish Sahoo5

1Senior Resident, Department of Psychiatry, NSCB Medical College, Jabalpur, Madhya Pradesh.
2Assistant Professor, Department of Psychiatry, NSCB Medical College, Jabalpur, Madhya Pradesh.
3Senior Resident, Department of Psychiatry, NSCB Medical College, Jabalpur, Madhya Pradesh.
4Medical Officer, Department of PH & FW, Jabalpur, Madhya Pradesh.
5Junior Resident, Department of Psychiatry, NSCB Medical College, Jabalpur, Madhya Pradesh.

Corresponding Author:
Dr. Aftab Ahmed Khan,
Assistant Professor,
Department of Psychiatry,
NSCB Medical College,
Jabalpur,
Madhya Pradesh.
E-mail: draftab79@yahoo.com

ABSTRACT

BACKGROUND

Paediatric Bipolar Disorder (BD) is a highly morbid paediatric psychiatric disease, consistently associated with family history of mood disorders and associated with high levels of morbidity and disability and with a greater risk of suicide. While there is a general consensus on the symptomatology of depression in childhood, the phenomenology of paediatric mania is still highly debated and the course and long-term outcomes of paediatric BD still need to be clarified.

Keywords

Bipolar disorder, Mania, children.

How to cite this article

Agrawal S, Khan AA, Mittal G, et al. First-episode mania in a 9-year-old child - A case report. Journal of Research in Psychiatry and Behavioural Sciences 2016; Vol. 2, Issue 2, July-December 2016; Page:10-11.

Background

Paediatric bipolar disorder is among the most controversial areas of child and adolescent psychiatry, mainly because of the limitations in diagnosis.[1,2]

Frequent overlap and presence of comorbid conditions like ADHD, conduct disorder, medical conditions make it difficult to diagnose this condition.[3]

The view that paediatric bipolar disorder is rare, more so paediatric mania[4] is being increasingly challenged by evidence from systematic research. Onset of this disorder before the age of 12 years, previously thought to be non–existent, is now becoming more accepted.[4,5] Paediatric mania is characterised by irritable mood, non-episodic course, chronic rapid cycling and presence of mixed states.[6] A review of available literature reveals that paediatric mania seldom presents with a euphoric mood.[4] The onset of this disorder has been reported in children as young as 5 years.[6] In India the youngest report is of a 6-year-old girl.[7] It is usually known to be uncommon illness in children and the controversies regarding the diagnosis and treatment issues are present resulting in misdiagnosis and management of the child. Here forth is presented a case report of bipolar affective disorder first episode mania in a 9-year-old boy who responded well with mood stabilisers and low dose antipsychotics. Informed consent taken from patient and his father.

CASE REPORT

A 9-year-old male patient from urban background, middle socio-economic status, student of 5th standard presented to psychiatric opd of nscb Medical College, jabalpur by his parents from whom reliable and adequate information was obtained. According to informants, patient had fever with cough and vomiting 10 days back for which he took primary treatment by physician and improved in 2-3 days. Patient started going to school and was well for about 1 week, but about 3 days before presenting to us, patients started having decreased sleep (total duration reduced to 4-5 hours with early awakening at around 4 am in morning). Parents also noticed a change in his behaviour, like increased activities. His sleep decreased and he started cleaning his room 6 a.m. in morning. He was playing with his dog saying that this is a tiger and i am a hunter. He started throwing utensils out of the kitchen saying that these are of no use and I will buy new ones for you. He was excessively talkative continuously singing like "mummy laal hain, papa neele hain, bade papa me current hai" etc. He was talking with lots of gestures, making faces and moving his hands in air. When his parents tried to send him to school, he said he doesn’t need education as he is a hunter. There was no history suggestive of any organic illness, depressed mood, or any schizophrenic symptoms or substance abuse. The past history and family history were negative for any psychiatric illnesses. On mental status examination, his mood was predominantly elated, psychomotor activity was increased, the tone, tempo and volume of speech were increased, with pressure of speech at times. Delusion of grandiosity was present. All investigations like routine haemogram, urine examination, CT scan and an EEG revealed no abnormality. A diagnosis of first-episode mania was made and the patient was put on Valproic acid 300 mg BD, risperidone 3 mg and olanzapine 5 mg/day dose. Patient developed EPS with incontinence on 2nd day and his risperidone was reduced to 1 mg/day and olanzapine was removed. Patient showed significant improvement in 10 days and was advised to continue same treatment for 15 days until subsequent followup.

DISCUSSION

Bipolar disorder in children is difficult to diagnose because of considerable overlap of symptoms with disorders such as ADHD, conduct disorder and substance abuse disorder. It is also viewed as a distinct entity because of its differences from adult onset variant[8,9] in terms of symptomatology, duration and cause of illness, presence of comorbidity, and management.[5] The present case clearly meets the ICD-10 diagnostic criteria of first-episode mania. Paediatric onset mania is rarely found to have euphoric mood, usually has a non-episodic course, is rapidly cycling and presents in a mixed manic state.[4] The case we report here is unique as it presented with typical adult-onset manic symptoms of elation with grandiosity. Many a time, ADHD appears to be an important differential diagnosis;[9] however, our case had no distractibility, motor hyperactivity or attention abnormality prior to the onset of illness or after the remission of illness. Management of bipolar disorder in paediatric age group is also a debatable issue with opinions ranging from antipsychotic to mood stabilisers.[9] In our case, patient responded very well to a combination of mood stabiliser and antipsychotic emphasising the role of both in management of such patients although more prospective study with larger number of patients required for proper management, that is also a limitation of our study. Children with mania may be relatively uncommon in outpatient settings, but clinical practice suggests that they may account for a substantial number of childhood psychiatric hospitalisations and manifest with chronic psychosocial disability.

REFERENCES

  1. Geller B, Zimerman B, Williams M, et al. Phenomenology of prepubertal and early adolescent bipolar disorder: examples of elated mood, grandiose behaviors, decreased need for sleep, racing thoughts and hypersexuality. J Child Adolesc Psychopharmacol 2002;12(1):3-9.
  2. Wozniak J, Biederman J. Childhood mania: insights into diagnostic and treatment issues. J Assoc Acad Minor Phys 1997;8(4):78-84.
  3. Weller RA, Weller EB, Tucker SG, et al. Mania in prepubertal children: has it been underdiagnosed? J Affective Disorder 1986;11(2):151-4.
  4. Biederman J, Mick E, Faraone SV, et al. Pediatric mania: a developmental subtype of bipolar disorder? Biol Psychiatry 2000;48(6):458-66.
  5. Aravind VK, Krishnaram VD. Pediatric bipolar disorder. Indian J Psychol med 2009;31(2):88-91.
  6. Dilsaver SC, Akiskal SH. Preschool-onset mania: incidence, phenomenology and family history. J of Affective disorder 2004;82(Suppl 1):S35-43.
  7. Aslam M, Khan AW. Mania in a six year old child. JK Science 2003;5(2):86-8.
  8. Luby J, Belden A. Defining and validating bipolar disorder in the preschool period. Dev Psychopathol 2006;18(4): 971-88.
  9. Biederman J. Early onset bipolar disorder. In: Sadock BJ, Sadock VA, (edr). 8th edn. Comprehensive text book of psychiatry. Lippincott Williams & Wilkins, New York 2005:3274-79.

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