Well Sony has Killzone and Microsoft has Halo but, what does Nintendo have? I see the Metroid Prime series as a chance for the Wii U to have an exclusive next-gen FPS with online multiplayer. However, the Metroid Prime series has since abandoned multiplayer as Metroid Prime Echoes and Prime Hunters were the last to have a multiplayer mode. The Wii U right now needs "killer apps" or games that would sell the console and I think a Metroid Prime with online multiplayer could be that game.
With the loss of friend codes in the Wii U it will be much easier to establish a serious online FPS community because you would be able to play anybody with no issues unlike the Wii. Though I'm not saying make Metroid Prime's multiplayer follow Halo and Killzone's footsteps exactly. Of course different weapons/ abilities would be in the multiplayer to separate it from other FPS's. Use of the attacks like the screw attack and power bomb would make the multiplayer feel more like Metroid. I think if Metroid emulated some of the things Killzone and Halo did with their multiplayer it could get more established in the world of FPS's.
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