Significant
by Jeff
Image text: 'So, uh, we did the green study again and got no link. It was probably a--' 'RESEARCH CONFLICTED ON GREEN JELLY BEAN/ACNE LINK; MORE STUDY RECOMMENDED!'
In this comic, Megan and Cueball come to see some scientists to investigate their theory that jelly beans cause acne. The scientists of course do not want to stop playing the addictive game Minecraft (which has been referenced in previous xkcds). I can attest to the fact that it is impossible to stop playing that game.
When the scientists come back and say there is no link between jelly beans and acne, Megan and Cueball have heard that it is specific colors that cause acne. So, the scientists tear themselves away from Minecraft again and study each and every color (including mauve and turquoise - I didn't know those were real colors for jelly beans). Green is the only color that has any link. So, obviously the news blows the coverage out of control, even though as we see in the image text that the green jelly beans study may have been a coincidence.
But, of course, the news coverage in all caps in the image text blows it out of proportion again.
EDIT: Commenters Marco and Aron B. have the real joke in the comments, hit the link and check them out.
Wisdom Teeth
by Jeff
Image text: I heard the general anesthesia drugs can cause amnesia, so when I woke up mid-extraction I started taking notes on my hand so I'd remember things later. I managed 'AWAKE BUT EVERYTHING OK' before the dental assistant managed to find and confiscate all my pens.
In this comic, Cueball decides it is finally time to play the game Minecraft (which is quite addicting) because he is getting his wisdom teeth out. Minecraft describes itself on its website as: "a game about placing blocks to build anything you can imagine. At night monsters come out, make sure to build a shelter before that happens." In the fourth frame, we see that instead of building anything, Cueball has flattened the continent out. I'm not sure what the block item in the lower right hand corner of the 4th frame is because I haven't played Minecraft. Anyone have any ideas?
Cueball makes a strange choice to flatten the continent because of all the painkiller drugs he is on after the wisdom teeth extraction. In the image text, because Cueball fears amnesia and memory loss from the anesthesia drugs, he writes information on his hand similar to the way the protagonist does in the movie Memento.