Common cold cure aims to blow out symptoms
CHASING CURES | CBC News examines how close we are to finding cures for aging, obesity, diabetes, the common cold and cancer in a series of special reports
CBC News
Posted: Jan 3, 2012 5:55 AM ET
Last Updated: Jan 3, 2012 4:27 PM ET
Related
Related Links
External Links
(Note:CBC does not endorse and is not responsible for the content of external links.)
Chasing cures
- Aging slowed in mice with supplement mix
- Type 1 diabetes prevention 'better than cure'
- Common cold cure aims to blow out symptoms
- QUIZ | Uncommon facts about the common cold
- Drug starves fat cells in obese monkeys
- Hip implant lawsuits pile up
- Recalled defibrillator linked to rush to market
- BY THE NUMBERS | Cancer rates in Canada
- Curing cancer: a reality check
- Testing exercise as breast cancer prevention
- Top 10 apps for health, fitness and nutrition
Could the low-grade misery of a runny nose, sore throat and heavy head that signal the common cold be snuffed out?
The University of Calgary is one of only two places in North America that are approved to infect people with cold viruses to study how their immune systems respond. The goal is to make respiratory infections such as the cold less dangerous to people with asthma and other lung diseases.
The lead researcher says a happy outcome would be making colds symptom-free for everyone.
"My argument would be if you have close to a symptom-free cold, that's about as good a cure as we’re ever going to get," said David Proud, a professor of physiology and pharmacology at the University of Calgary.
"We don't want to stop you from making immunity to that virus, it will protect you the next time. But we don't want you to have the worst of the symptoms."
Proud's interest in the 200-plus viruses that cause the common cold isn't just in run-of-the-mill colds.
Rather, Proud is concerned about how colds can trigger attacks of lower-airway diseases such as asthma, cystic fibrosis, bronchitis and emphysema, which can be life-threatening.The common cold costs billions of dollars to society in lost days of work and school. (iStock)
In Canada, exacerbation of chronic obstructive pulmonary disorder or COPD is the most common reason for hospitalization of adults, with an average stay of two weeks, he noted.
At Proud's laboratory, researchers are looking for substances the body makes when it tries to fight off the sniffles.
"What we've been working on is trying to understand which of those anti-viral molecules are most important," said Proud.
If "we can find a way to boost how you produce them or maybe supplement them with some sort of spray system, that would allow you to have a better immune response."
In January, Proud and his team will start infecting people with cold virus as part of an experiment.
Last month, Proud used a dropper and then a spray to deliver droplets of a cold virus into the nose of volunteer Jonathan Pelikan.
In the name of science, Pelikan agreed to be infected with a cold and allowed CBC to follow his progress. After 48 hours, he developed cold symptoms.
"I definitely have the sniffles," Pelikan said, wiping his nose.
Herbal remedies for cold
Pelikan turned to his mom's prescription of chicken soup, rest and fluids to fight his congestion and sore throat.
Studies suggest that herbal remedies such as echinacea and zinc have only a modest effect on colds, said Dr. Shelly McNeil, an infectious disease specialist at Dalhousie University in Halifax.
"They all have some evidence in the lab and even some in people that they do modulate the way the immune system responds to viruses," said McNeil, who is studying the effectiveness of the cold remedy Cold-Fx for children.
"The problem with them is, they're not regulated as tightly as drugs, so it's hard to know what you're getting."
Over-the-counter products treat individual symptoms such as a runny nose, which Proud calls a piecemeal approach instead of a cure.
Most current herbal products, if they show any benefit, reduce cold duration by two or three days at the most, McNeil said.
Proud and his team plan to study Pelikan and other volunteers to check if the changes they see in test tube models actually occur in patients. If so, that will give them clues to render colds symptom-free.
This week CBC News reports on the search for cures for aging, Type 1 diabetes, the common cold, obesity and cancer on CBC Radio One, CBC News Network, The National and at cbc.ca/news/health/.
With files from CBC's Pauline DakinShare Tools
Top News Headlines
- Arab League set to keep monitors in Syria
- Foreign ministers from the Arab League are meeting in Cairo amid further reports of violence in Syria, as they discuss findings from their month-long observer mission in the country. more »
- Croatia holds referendum on joining EU
- Croatians go to the polls Sunday in a nationwide referendum on whether to join the European Union — a test of how much the debt-stricken 27-nation bloc has lost its appeal among potential new members. more »
- 2 missing after B.C. mill explosion
- Two people are unaccounted for after a fire and explosion tore through a sawmill east of Burns Lake, B.C., on Friday, officials say. more »
- Ex-Penn State coach Paterno in serious condition
- A family spokesman says former Penn State coach Joe Paterno, who is battling lung cancer, is in serious condition after experiencing health complications. more »
Latest Health News Headlines
- Helmets for tobogganing kids get crash tests
- A Canadian study suggests young children should wear helmets while tobogganing, but concludes there's no clear answer about what type of headgear works best. more »
- Bird flu mutation studies paused to decide next steps
- Scientists studying a more dangerous version of the H5N1 bird flu virus say they'll stop their experiments for 60 days. more »
- Untreated insomnia risks other health woes
- Insomnia is the most common sleep disorder but it often goes untreated, which increases the risk for anxiety, depression and heart failure, a review concludes. more »
- Military stress ball contract squashed by MacKay
- Defence Minister Peter MacKay squashes a plan to purchase 20,000 orange stress balls for the military saying it is an unnecessary expenses, according to his spokesman. more »
FEATURED HEALTH
- Gingrich wins big in South Carolina primary
- 2 missing after B.C. mill explosion
- Italian cruise ship divers find 12th victim
- Catchphrase involving Canada hot in Brazil
- Gingrich blasts Obama in victory speech
- Sarah Burke's medical bills covered by donations
- Edmonton condo renters see some financial relief after fire
- 'Extinct' monkey still lives in Borneo
- Weather warnings, travel advisories issued in B.C.