 |
 |
 |
|
More interleague records: 2008 Team-by-team | Club records | Play leaders | Wins by league & attendance
| American League | W-L | AVG | HR | R | ERA |
| Baltimore Orioles | 11-7 | .277 | 23 | 96 | 4.20 |
| Boston Red Sox | 11-7 | .282 | 27 | 92 | 3.64 |
| Chicago White Sox | 12-6 | .293 | 30 | 103 | 3.42 |
| Cleveland Indians | 6-12 | .247 | 17 | 69 | 4.47 |
| Detroit Tigers | 13-5 | .306 | 24 | 93 | 3.79 |
| Kansas City Royals | 13-5 | .281 | 17 | 101 | 3.68 |
| L.A. Angeles of Anaheim | 10-8 | .260 | 11 | 73 | 3.09 |
| Minnesota Twins | 14-4 | .281 | 15 | 98 | 2.44 |
| New York Yankees | 10-7 | .268 | 18 | 87 | 4.11 |
| Oakland Athletics | 10-8 | .242 | 15 | 73 | 3.49 |
| Seattle Mariners | 9-9 | .286 | 10 | 83 | 3.96 |
| Tampa Bay Rays | 12-6 | .290 | 23 | 98 | 3.21 |
| Texas Rangers | 10-8 | .270 | 27 | 99 | 4.04 |
| Toronto Blue Jays | 8-10 | .264 | 19 | 82 | 4.22 |
| National League | W-L | AVG | HR | R | ERA |
| Arizona Diamondbacks | 6-9 | .208 | 7 | 43 | 4.67 |
| Atlanta Braves | 8-7 | .269 | 12 | 64 | 3.38 |
| Chicago Cubs | 6-9 | .287 | 18 | 71 | 5.20 |
| Cincinnati Reds | 9-6 | .232 | 17 | 54 | 4.20 |
| Colorado Rockies | 7-8 | .274 | 16 | 61 | 3.79 |
| Florida Marlins | 5-10 | .239 | 18 | 68 | 5.39 |
| Houston Astros | 7-11 | .261 | 16 | 69 | 5.03 |
| Los Angeles Dodgers | 5-10 | .214 | 9 | 44 | 3.92 |
| Milwaukee Brewers | 7-8 | .251 | 30 | 72 | 4.47 |
| New York Mets | 9-6 | .274 | 19 | 81 | 4.13 |
| Philadelphia Phillies | 3-15 | .220 | 15 | 27 | 4.90 |
| Pittsburgh Pirates | 5-9 | .247 | 16 | 69 | 6.73 |
| St. Louis Cardinals | 7-8 | .288 | 20 | 69 | 4.05 |
| San Diego Padres | 3-15 | .250 | 17 | 59 | 4.90 |
| San Francisco Giants | 6-12 | .245 | 6 | 67 | 4.44 |
| Washington Nationals | 8-10 | .251 | 15 | 62 | 4.31 |
